Mirena® (Levonorgestrel intrauterine system): A successful novel drug delivery option in contraception

Susan Rose; Angela Chaudhari; C. Matthew Peterson

doi:10.1016/j.addr.2009.04.022

Mirena^® (Levonorgestrel intrauterine system): A successful novel drug delivery option in contraception

Susan Rose^*, Angela Chaudhari, C. Matthew Peterson

^*Corresponding author for this work

Obstetrics and Gynecology

Research output: Contribution to journal › Review article › peer-review

38 Scopus citations

Abstract

This manuscript serves as a review of Mirena^®, the levonorgestrel intrauterine system (LNG IUS) as a very successful drug delivery system. The LNG IUS has a very high contraceptive efficacy rate, and low rates of patient discontinuation. In addition to its contraceptive benefits, most users experience a decrease in menstrual bleeding over the 5 years of use. LNG IUS has also been used for management of menorrhagia, dysmenorrhea, adenomyosis, and endometrial hyperplasia in some cases. The LNG IUS provides long term efficacy, high rates of compliance, rapid return to fertility, and minimal adverse effects during use.

Original language	English (US)
Pages (from-to)	808-812
Number of pages	5
Journal	Advanced Drug Delivery Reviews
Volume	61
Issue number	10
DOIs	https://doi.org/10.1016/j.addr.2009.04.022
State	Published - Aug 10 2009

Keywords

Contraception
Copper-T IUD
Endometrial hyperplasia
Intrauterine device
Menorrhagia
Progesterone

ASJC Scopus subject areas

Pharmaceutical Science

Access to Document

10.1016/j.addr.2009.04.022

Cite this

@article{d5640abf07e24aa3819990f7030c8a48,

title = "Mirena{\textregistered} (Levonorgestrel intrauterine system): A successful novel drug delivery option in contraception",

abstract = "This manuscript serves as a review of Mirena{\textregistered}, the levonorgestrel intrauterine system (LNG IUS) as a very successful drug delivery system. The LNG IUS has a very high contraceptive efficacy rate, and low rates of patient discontinuation. In addition to its contraceptive benefits, most users experience a decrease in menstrual bleeding over the 5 years of use. LNG IUS has also been used for management of menorrhagia, dysmenorrhea, adenomyosis, and endometrial hyperplasia in some cases. The LNG IUS provides long term efficacy, high rates of compliance, rapid return to fertility, and minimal adverse effects during use.",

keywords = "Contraception, Copper-T IUD, Endometrial hyperplasia, Intrauterine device, Menorrhagia, Progesterone",

author = "Susan Rose and Angela Chaudhari and Peterson, {C. Matthew}",

year = "2009",

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doi = "10.1016/j.addr.2009.04.022",

language = "English (US)",

volume = "61",

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journal = "Advanced Drug Delivery Reviews",

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T1 - Mirena® (Levonorgestrel intrauterine system)

T2 - A successful novel drug delivery option in contraception

AU - Rose, Susan

AU - Chaudhari, Angela

AU - Peterson, C. Matthew

PY - 2009/8/10

Y1 - 2009/8/10

N2 - This manuscript serves as a review of Mirena®, the levonorgestrel intrauterine system (LNG IUS) as a very successful drug delivery system. The LNG IUS has a very high contraceptive efficacy rate, and low rates of patient discontinuation. In addition to its contraceptive benefits, most users experience a decrease in menstrual bleeding over the 5 years of use. LNG IUS has also been used for management of menorrhagia, dysmenorrhea, adenomyosis, and endometrial hyperplasia in some cases. The LNG IUS provides long term efficacy, high rates of compliance, rapid return to fertility, and minimal adverse effects during use.

AB - This manuscript serves as a review of Mirena®, the levonorgestrel intrauterine system (LNG IUS) as a very successful drug delivery system. The LNG IUS has a very high contraceptive efficacy rate, and low rates of patient discontinuation. In addition to its contraceptive benefits, most users experience a decrease in menstrual bleeding over the 5 years of use. LNG IUS has also been used for management of menorrhagia, dysmenorrhea, adenomyosis, and endometrial hyperplasia in some cases. The LNG IUS provides long term efficacy, high rates of compliance, rapid return to fertility, and minimal adverse effects during use.

KW - Contraception

KW - Copper-T IUD

KW - Endometrial hyperplasia

KW - Intrauterine device

KW - Menorrhagia

KW - Progesterone

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