Mitochondrial anchors: Positioning mitochondria and more

Lauren M. Kraft, Laura L. Lackner*

*Corresponding author for this work

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

The shape and position of mitochondria are intimately connected to both mitochondrial and cellular function. Mitochondrial anchors play a central role in mitochondrial positioning by exerting spatial, temporal, and contextual control over the cellular position of the organelle. Investigations into the molecular mechanisms of mitochondrial anchoring are still in the early stages, and we are beginning to appreciate the number and variety of anchors that exist. From the insight gained thus far, it is clear that mitochondrial anchoring has functional and physiological consequences that extend beyond mitochondrial positioning to other critical cellular processes.

Original languageEnglish (US)
Pages (from-to)2-8
Number of pages7
JournalBiochemical and Biophysical Research Communications
Volume500
Issue number1
DOIs
StatePublished - May 27 2018

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Keywords

  • Mitochondrial anchors
  • Mitochondrial distribution
  • Mitochondrial positioning
  • Mitochondrial tethers

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Molecular Biology
  • Cell Biology

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