Recent evidence supports the notion that mitochondrial metabolism is necessary for T cell activation, proliferation, and function. Mitochondrial metabolism supports T cell anabolism by providing key metabolites for macromolecule synthesis and generating metabolites for T cell function. In this review, we focus on how mitochondrial metabolism controls conventional and regulatory T cell fates and function.
|Original language||English (US)|
|Number of pages||22|
|Journal||Annual Review of Immunology|
|State||Published - Apr 26 2021|
- TCA cycle
ASJC Scopus subject areas
- Immunology and Allergy