This paper presents a mixture model which combines features of the usual Cox proportional hazards model with those of a class of models, known as mixtures-of-experts. The resulting model is more flexible than the usual Cox model in the sense that the log hazard ratio is allowed to vary non-linearly as a function of the covariates. Thus it provides a flexible approach to both modelling survival data and model checking. The method is illustrated with simulated data, as well as with multiple myeloma data.
|Original language||English (US)|
|Number of pages||13|
|Journal||Statistics in Medicine|
|State||Published - May 15 1999|
ASJC Scopus subject areas
- Statistics and Probability