Modality independence of word comprehension

James R. Booth*, Douglas D. Burman, Joel R. Meyer, Darren R. Gitelman, Todd B. Parrish, M. Marsel Mesulam

*Corresponding author for this work

Research output: Contribution to journalArticle

180 Scopus citations

Abstract

Functional magnetic resonance imaging (fMRI) was used to examine the functional anatomy of word comprehension in the auditory and visual modalities of presentation. We asked our subjects to determine if word pairs were semantically associated (e.g., table, chair) and compared this to a reference task where they were asked to judge whether word pairs rhymed (e.g., bank, tank). This comparison showed task-specific and modality-independent activation for semantic processing in the heteromodal cortices of the left inferior frontal gyrus (BA 46, 47) and left middle temporal gyrus (BA 21). There were also modality-specific activations in the fusiform gyrus (BA 37) for written words and in the superior temporal gyrus (BA 22) for spoken words. Our findings are consistent with the hypothesis that word form recognition (lexical encoding) occurs in unimodal cortices and that heteromodal brain regions in the anterior as well as posterior components of the language network subserve word comprehension (semantic decoding).

Original languageEnglish (US)
Pages (from-to)251-261
Number of pages11
JournalHuman Brain Mapping
Volume16
Issue number4
DOIs
StatePublished - 2002

Keywords

  • Auditory
  • Lexical
  • Meaning
  • Semantic
  • Spoken
  • Visual
  • Written
  • fMRI

ASJC Scopus subject areas

  • Anatomy
  • Radiological and Ultrasound Technology
  • Radiology Nuclear Medicine and imaging
  • Neurology
  • Clinical Neurology

Fingerprint Dive into the research topics of 'Modality independence of word comprehension'. Together they form a unique fingerprint.

  • Cite this

    Booth, J. R., Burman, D. D., Meyer, J. R., Gitelman, D. R., Parrish, T. B., & Mesulam, M. M. (2002). Modality independence of word comprehension. Human Brain Mapping, 16(4), 251-261. https://doi.org/10.1002/hbm.10054