TY - JOUR
T1 - Model-free deconvolution techniques for estimating vascular transport functions
AU - Bronikowski, Thomas A.
AU - Dawson, Christopher A.
AU - Linehan, John H.
N1 - Funding Information:
This work was supported by the Veterans Administration and Grant HL 19298 from the National Heart, Lung and Blood Institute. The authors would like to thank Mary P. McDermott and Catherine A. Walther for typing the manuscript.
PY - 1983/9
Y1 - 1983/9
N2 - In this paper we present two methods which can be used to numerically deconvolve indicator dilution curves to obtain vascular transport functions. In the first method, direct algebraic deconvolution is made stable and practical by the damped least squares method. The second method involves a time-shift of the output curve which is based on the first and second moments of the input and output curves. This method is stable, computationally simple and can provide reasonable estimates of the transport function.
AB - In this paper we present two methods which can be used to numerically deconvolve indicator dilution curves to obtain vascular transport functions. In the first method, direct algebraic deconvolution is made stable and practical by the damped least squares method. The second method involves a time-shift of the output curve which is based on the first and second moments of the input and output curves. This method is stable, computationally simple and can provide reasonable estimates of the transport function.
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U2 - 10.1016/0020-7101(83)90024-7
DO - 10.1016/0020-7101(83)90024-7
M3 - Article
C2 - 6642751
AN - SCOPUS:0021076216
VL - 14
SP - 411
EP - 429
JO - International Journal of Medical Informatics
JF - International Journal of Medical Informatics
SN - 1386-5056
IS - 5
ER -