Model substrates for controlling and understanding the interactions of cells with materials

Milan Mrksich*

*Corresponding author for this work

Research output: Contribution to journalConference articlepeer-review

Abstract

An overview is given on the use of self-assembled monolayers of alkanethiolates on gold as model substrates for studying and controlling the interactions of proteins and cells with non-natural materials. The design of dynamic substrates that can alter, in real time, the presentation of ligands to an attached cell was also presented. Examples are given which establish that self-assembled monolayers of alkanethiolates on gold are an excellent model system for controlling the adhesion of cells and found wide use both in fundamental studies for biology and in applied targets for biotechnology.

Original languageEnglish (US)
JournalAnnals of Biomedical Engineering
Volume28
Issue numberSUPPL. 1
StatePublished - Dec 1 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

ASJC Scopus subject areas

  • Biomedical Engineering

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