Modeling Brain Pathology of Niemann-Pick Disease Type C Using Patient-Derived Neurons

Keyphrases

• Cortical Neurons 100%
• Induced Pluripotent Stem Cells (iPSCs) 100%
• Patient-derived 100%
• Pathological Features 100%
• NP-C 100%
• Alzheimer's Disease 50%
• Autosomal Recessive 50%
• Mechanistic Studies 50%
• Brain Tissue 50%
• Histological Markers 50%
• Human Induced Pluripotent Stem Cell-derived Neurons 50%
• Amyloid Deposition 50%
• Stem Cell-derived 50%
• Dystrophic Neurites 50%
• Postmortem Brain 50%
• Lysosomal Storage Disease 50%
• Neurofibrillary Tangles 50%
• Biochemical Markers 50%
• Therapeutic Study 50%
• Progressive Neurodegeneration 50%
• Phosphorylated tau 50%
• Amyloid Precursor Protein 50%
• Axonal Spheroids 50%

Biochemistry, Genetics and Molecular Biology

• Induced Pluripotent Stem Cell 100%
• Niemann-Pick Disease 100%
• Neurofibrillary Tangle 50%
• Tau 50%
• Lysosomal Storage Disease 50%
• Tumor Spheroid 50%
• Autosomal Recessive Inheritance 50%
• Amyloid Precursor Protein 50%
• Amyloid Protein 50%

Neuroscience

• Stem Cell 100%
• Pick's Disease 100%
• Amyloid Precursor Protein 50%
• Amyloid Protein 50%
• Alzheimer's Disease 50%
• Neurodegeneration 50%
• Neurite 50%