Models of astrocytoma

Demirkan B. Gürsel, Karlyne M. Reilly*

*Corresponding author for this work

Research output: Contribution to journalReview article

Abstract

Astrocytomas are the most common primary tumor affecting the adult central nervous system (CNS). Owing to their diffusely infiltrative nature, there are currently no effective therapies. New approaches to targeting signal transduction pathways in astrocytomas are offering some hope for effective treatment. This article will review the different model systems that can be used to identify new therapeutic targets and test their effectiveness against astrocytoma.

Original languageEnglish (US)
Pages (from-to)77-83
Number of pages7
JournalDrug Discovery Today: Disease Models
Volume2
Issue number1
DOIs
StatePublished - Jul 18 2005

ASJC Scopus subject areas

  • Drug Discovery
  • Molecular Medicine

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