Modernizing the World Health Organization List of Essential Medicines for Preventing and Controlling Cardiovascular Diseases

Sandeep P. Kishore*, Evan Blank, David J. Heller, Amisha Patel, Alexander Peters, Matthew Price, Mahesh Vidula, Valentin Fuster, Oyere Onuma, Mark D. Huffman, Rajesh Vedanthan

*Corresponding author for this work

Research output: Contribution to journalReview article

11 Scopus citations

Abstract

The World Health Organization (WHO) Model List of Essential Medicines (EML) is a key tool for improving global access to medicines for all conditions, including cardiovascular diseases (CVDs). The WHO EML is used by member states to determine their national essential medicine lists and policies and to guide procurement of medicines in the public sector. Here, we describe our efforts to modernize the EML for global CVD prevention and control. We review the recent history of applications to add, delete, and change indications for CVD medicines, with the aim of aligning the list with contemporary clinical practice guidelines. We have identified 4 issues that affect decisions for the EML and may strengthen future applications: 1) cost and cost-effectiveness; 2) presence in clinical practice guidelines; 3) feedback loops; and 4) community engagement. We share our lessons to stimulate others in the global CVD community to embark on similar efforts.

Original languageEnglish (US)
Pages (from-to)564-574
Number of pages11
JournalJournal of the American College of Cardiology
Volume71
Issue number5
DOIs
StatePublished - Feb 6 2018

Keywords

  • NCDs
  • WHO Essential Medicines List
  • cardiovascular disease
  • essential medicines

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine

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    Kishore, S. P., Blank, E., Heller, D. J., Patel, A., Peters, A., Price, M., Vidula, M., Fuster, V., Onuma, O., Huffman, M. D., & Vedanthan, R. (2018). Modernizing the World Health Organization List of Essential Medicines for Preventing and Controlling Cardiovascular Diseases. Journal of the American College of Cardiology, 71(5), 564-574. https://doi.org/10.1016/j.jacc.2017.11.056