Modulating the activity of neural crest regulatory factors

Kimberly M. Taylor*, Carole LaBonne

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations

Abstract

Substantial progress has been made in defining the regulatory factors involved in generating multipotent neural crest cells at the neural plate border of vertebrate embryos, controlling the onset of their migratory behavior, and directing their differentiation into one of a diverse array of derivatives. Growing evidence suggests that these factors function as a complex network, in some cases displaying overlapping functions and cross-regulatory interactions. Mechanisms are emerging for how some of these regulatory components are controlled post-translationally and the extent to which their activities are conserved across species.

Original languageEnglish (US)
Pages (from-to)326-331
Number of pages6
JournalCurrent Opinion in Genetics and Development
Volume17
Issue number4
DOIs
StatePublished - Aug 2007

ASJC Scopus subject areas

  • Genetics
  • Developmental Biology

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