Molecular Assessment of Thyroid Nodules

Mayumi Endo*, Dina M. Elaraj, Neda A. Moatamed, Richard T. Kloos

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations


Our understanding of the genomics of benign and malignant thyroid nodules has advanced rapidly, and so have the applications that utilize this information for clinical decision-making. Not long ago, it was “cutting-edge” medicine to test for a single genomic variant. Now, everyday practitioners have access to gene panels and genomic classifiers that utilize hundreds and thousands of genes. Here, we discuss current cytological nomenclature of thyroid aspirates, review cellular genomics, discuss current genomic tests for cytologically indeterminate nodules, consider surgical decision-making, explore the potential role of genomics among suspicious and malignant cytology categories, and consider future directions.

Original languageEnglish (US)
Title of host publicationInnovations in Modern Endocrine Surgery
PublisherSpringer International Publishing
Number of pages34
ISBN (Electronic)9783030739515
ISBN (Print)9783030739508
StatePublished - Jan 1 2021


  • Genomics
  • Molecular diagnostics
  • Molecular testing
  • Thyroid cancer
  • Thyroid nodule

ASJC Scopus subject areas

  • Medicine(all)


Dive into the research topics of 'Molecular Assessment of Thyroid Nodules'. Together they form a unique fingerprint.

Cite this