Molecular basis for multiple forms of LDH‐X

Erwin Goldberg*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The guinea pig has three molecular species of LDH‐X which are inhibited by antiserum directed against the C subunit. Only two of these are selectively inhibited by anti‐A polypeptide antiserum. Heterotetramers produced by in vitro dissociation and recombination of isozymes and containing B‐C subunit combinations are selectively inhibited only by the anti‐C antiserum. Therefore, the subunit composition of these multiple forms of LDH‐X are: CCCC; CCCA; CCAA. Similarly, rat testes contain two forms of LDH‐X which can be described as CCCC and CCCA tetramers.

Original languageEnglish (US)
Pages (from-to)273-278
Number of pages6
JournalJournal of Experimental Zoology
Volume186
Issue number3
DOIs
StatePublished - Jan 1 1973

ASJC Scopus subject areas

  • Animal Science and Zoology

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