Molecular biology of transplantation

Alan M. Krensky*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Scopus citations

Abstract

The past decade has witnessed an explosion in our understanding of the molecules involved in transplant rejection and acceptance. This review highlights our current understanding of antigen recognition, signal transduction, and effector mechanisms of the immune system. Such information has proven important in understanding the action of immunosuppressive drugs and will prove useful in the design of new immunotherapies. Copyright (C) 2000 S. Karger AG, Basel.

Original languageEnglish (US)
Pages (from-to)260-265
Number of pages6
JournalNephron
Volume86
Issue number3
DOIs
StatePublished - Jan 1 2000

Keywords

  • Adhesion molecules
  • Cytokines
  • Immunology
  • Immunosuppression
  • Lymphocytes
  • Molecular biology
  • Rejection
  • Tolerance
  • Transplantation

ASJC Scopus subject areas

  • Physiology
  • Nephrology
  • Physiology (medical)
  • Urology

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