Molecular components of the adherens junction

Carien M. Niessen, Cara J. Gottardi*

*Corresponding author for this work

Research output: Contribution to journalReview article

164 Scopus citations

Abstract

Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins. The molecular machineries that organize these adhesion receptor complexes into higher order junction structures, and the functional consequences of this junctional organization will be discussed.

Original languageEnglish (US)
Pages (from-to)562-571
Number of pages10
JournalBiochimica et Biophysica Acta - Biomembranes
Volume1778
Issue number3
DOIs
StatePublished - Mar 1 2008

Keywords

  • Adhesion
  • Cadherin
  • Catenin
  • Nectin
  • Zonula adherens

ASJC Scopus subject areas

  • Biophysics
  • Biochemistry
  • Cell Biology

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