Abstract
Cancer can be viewed as a dynamic process driven by the cellular accumulation of genetic alterations that provide selective growth advantage. Such alterations can be classified as one of two fundamental types : acquired (cancer-affective, dominant) or eliminated (cancer suppressive, recessive). This review considers genetic alterations that occur during the development of the most common type of central nervous system tumour, glioma.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 631-644 |
| Number of pages | 14 |
| Journal | Cancer Surveys |
| Volume | 9 |
| Issue number | 4 |
| State | Published - 1990 |
Keywords
- RFLP analysis
- clonal evolution
- dominant
- loss of genetic information
- malignancy grade
- primary or secondary genetic alteration
- recessive
- tumour evolution
- tumour progression
- tumour suppression
ASJC Scopus subject areas
- Oncology
- Cancer Research
