Molecular genetics in the pediatric intensive care unit

Thomas P. Shanley*, Hector R. Wong

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

18 Scopus citations


Molecular genetics and genomics have become highly relevant tools in the field of pediatric critical care medicine. The most immediate examples involve the use of molecular genetics as routine diagnostic tests (eg, detection of herpes simplex virus by PCR). Perhaps the most exciting and promising examples involve the research efforts based in these fields, which hold the potential to gain novel insight regarding the complex mechanisms involved in critical illness. Ultimately, the generation of more comprehensive and fundamental knowledge can lead to the design of more effective and specific therapeutic strategies.

Original languageEnglish (US)
Pages (from-to)577-594
Number of pages18
JournalCritical Care Clinics
Issue number3
StatePublished - Jul 2003

ASJC Scopus subject areas

  • Critical Care and Intensive Care Medicine


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