Abstract
Molecular genetics and genomics have become highly relevant tools in the field of pediatric critical care medicine. The most immediate examples involve the use of molecular genetics as routine diagnostic tests (eg, detection of herpes simplex virus by PCR). Perhaps the most exciting and promising examples involve the research efforts based in these fields, which hold the potential to gain novel insight regarding the complex mechanisms involved in critical illness. Ultimately, the generation of more comprehensive and fundamental knowledge can lead to the design of more effective and specific therapeutic strategies.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 577-594 |
| Number of pages | 18 |
| Journal | Critical Care Clinics |
| Volume | 19 |
| Issue number | 3 |
| DOIs | |
| State | Published - Jul 2003 |
Funding
This work was supported by grants from the National Institutes of Health KO8 HL/AI04291 (T.P.S.) and RO1 GM61723 (H.R.W.)
ASJC Scopus subject areas
- Critical Care and Intensive Care Medicine