Molecular targets in breast cancer: Current status and future directions

M. Cristofanilli*, G. N. Hortobagyi

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations


Our increasing understanding of the pathophysiologic mechanisms of breast carcinogenesis has generated detailed information about the potential roles of specific biomolecular markers in this process. Furthermore, in the last few years the process of targeted drug design has become faster and more sophisticated, providing a variety of agents targeted at these molecules. In this review, we describe the most widely recognized molecular targets in breast cancer.

Original languageEnglish (US)
Pages (from-to)249-266
Number of pages18
JournalEndocrine-related cancer
Issue number4
StatePublished - Dec 2002

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Oncology
  • Endocrinology
  • Cancer Research

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