Monocyte chemoattractant protein-1 correlates with subcortical brain injury in HIV infection

A. B. Ragin*, Y. Wu, P. Storey, B. A. Cohen, R. R. Edelman, L. G. Epstein

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

29 Scopus citations

Abstract

Various biomarkers have been suggested as associative or predictive of HIV-associated neurocognitive impairment. Plasma levels of monocyte chemoattractant protein 1 (MCP-1), tumor necrosis factor α(TNF-α), and hematocrit were evaluated for relationships with diffusion tensor imaging measurements of centrum semiovale, caudate, and putamen. MCP-1 levels correlated with tissue status (mean diffusivity) in all examined regions. Plasma markers were also significantly correlated with anisotropy measurements in centrum semiovale (TNF-α) and putamen (hematocrit).

Original languageEnglish (US)
Pages (from-to)1255-1257
Number of pages3
JournalNeurology
Volume66
Issue number8
DOIs
StatePublished - Apr 2006

ASJC Scopus subject areas

  • Clinical Neurology

Fingerprint Dive into the research topics of 'Monocyte chemoattractant protein-1 correlates with subcortical brain injury in HIV infection'. Together they form a unique fingerprint.

Cite this