Morbidity and mortality following bone marrow transplantation: Predictive utility of pre-BMT affective functioning, compliance, and social support stability

James R. Rodrigue*, Timothy P. Pearman, Jan Moreb

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Scopus citations

Abstract

This study investigated the utility of 3 pretransplant psychological variables (affective functioning, compliance, social support stability) in predicting subsequent bone marrow transplantation (BMT) health outcomes. The pre-BMT psychological evaluations of 92 BMT recipients were coded along the specified psychological dimensions and used to predict post-BMT survival status and health-related quality of life. Data analyses showed that, in addition to medical risk status (low) and quality of the marrow graft (histocompatible), higher levels of pre-BMT affective functioning and social support stability significantly predicted survival status (i.e., alive) and higher levels of quality of life. These findings have important implications for the role of psychological assessment prior to BMT and the need for interventions designed to enhance psychological functioning and subsequent health outcomes following BMT.

Original languageEnglish (US)
Pages (from-to)241-254
Number of pages14
JournalInternational Journal of Behavioral Medicine
Volume6
Issue number3
DOIs
StatePublished - Jan 1 1999

Keywords

  • Bone marrow transplantation (BMT)
  • Psychological functioning
  • Quality of life

ASJC Scopus subject areas

  • Applied Psychology

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