Abstract
BACKGROUND AND OBJECTIVE: Advanced retinal imaging can improve understanding of retinal vein occlusion (RVO) pathology. The authors aimed to characterize the vascular pathology of RVO on en face optical coherence tomography (OCT) and OCT angiography (OCTA). PATIENT AND METHODS: This was a cross-sectional study including 17 eyes with RVO. The authors identified discordance between vasculature on en face OCT and flow on OCTA, which was correlated with structural findings at the corresponding location on OCT B-scans. RESULTS: Six eyes had vessels that were seen on OCT without flow on OCTA. The most clinically relevant finding was preserved inner retinal layers in areas where the en face OCT showed collaterals that appeared nonperfused on OCTA. CONCLUSIONS: The authors' findings indicate that collaterals can appear on en face OCT without flow on OCTA in RVO and may be associated with relatively preserved inner retinal structures. Clinicians should consider multimodal imaging to evaluate RVO, including both OCT and OCTA.
Original language | English (US) |
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Pages (from-to) | 392-396 |
Number of pages | 5 |
Journal | Ophthalmic Surgery Lasers and Imaging Retina |
Volume | 49 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2018 |
Funding
Originally submitted June 30, 2017. Revision received October 7, 2017. Accepted for publication November 1, 2017. This research was presented at the Association for Research in Vision and Ophthalmology annual meeting in March 2017. This work was funded by Research to Prevent Blindness, NY (Department of Ophthalmology, Northwestern University) and NIH 1DP3DK108248 (AAF). Optovue provided support in the form of supplying the optical coherence tomography angiography instrument. The sponsor or funding organizations had no role in the design or conduct of this research. The authors report no relevant financial disclosures. Address correspondence to Amani A. Fawzi, MD, Department of Ophthalmology, Northwestern University, 645 North Michigan Avenue, Suite 440, Chicago, IL 60611; email: [email protected]. doi: 10.3928/23258160-20180601-02
ASJC Scopus subject areas
- Surgery
- Ophthalmology