TY - GEN
T1 - MOSFET-embedded microcantilevers
T2 - 2006 5th IEEE Conference on Sensors
AU - Shekhawat, Gajendra
AU - Tark, Soo Hyun
AU - Dravid, Vinayak P.
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2006
Y1 - 2006
N2 - We recently introduced all-electronic label- and optics-free detection paradigm for biochemical binding events on metal-oxide semiconductor field-effect transistor (MOSFET)-embedded microcantilevers. Microcantilever bending as small as ∼5nm, leads to a measurable and reproducible change in the MOSFET drain current, which forms the basis for the microelectronics-based detection of molecular binding events. MOSFET-embedded microcantilevers are able to detect diverse probe-target binding events, ranging from DNA hybridization to protein-protein binding, at high sensitivity. Such label- and optics-free all-electronic MOSFET detection approach will bridge the current gap between integration of nano-bio nanostructures with microelectronics, and promises a universal and widely deployable bio-chem diagnosis platform, compatible with all the advantages of established CMOS technology for wide variety of biomolecular and chemical detection and diagnosis.
AB - We recently introduced all-electronic label- and optics-free detection paradigm for biochemical binding events on metal-oxide semiconductor field-effect transistor (MOSFET)-embedded microcantilevers. Microcantilever bending as small as ∼5nm, leads to a measurable and reproducible change in the MOSFET drain current, which forms the basis for the microelectronics-based detection of molecular binding events. MOSFET-embedded microcantilevers are able to detect diverse probe-target binding events, ranging from DNA hybridization to protein-protein binding, at high sensitivity. Such label- and optics-free all-electronic MOSFET detection approach will bridge the current gap between integration of nano-bio nanostructures with microelectronics, and promises a universal and widely deployable bio-chem diagnosis platform, compatible with all the advantages of established CMOS technology for wide variety of biomolecular and chemical detection and diagnosis.
UR - http://www.scopus.com/inward/record.url?scp=50149098417&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=50149098417&partnerID=8YFLogxK
U2 - 10.1109/ICSENS.2007.355576
DO - 10.1109/ICSENS.2007.355576
M3 - Conference contribution
AN - SCOPUS:50149098417
SN - 1424403766
SN - 9781424403769
T3 - Proceedings of IEEE Sensors
SP - 746
EP - 748
BT - 2006 5th IEEE Conference on Sensors
Y2 - 22 October 2006 through 25 October 2006
ER -