Motion-corrected free-breathing delayed enhancement imaging of myocardial infarction

Peter Kellman*, Andrew C. Larson, Li Yueh Hsu, Yiu Cho Chung, Orlando P. Simonetti, Elliot R. McVeigh, Andrew E. Arai

*Corresponding author for this work

Research output: Contribution to journalArticle

76 Scopus citations

Abstract

Following administration of Gd-DTPA, infarcted myocardium exhibits delayed enhancement and can be imaged using an inversion-recovery sequence. A conventional segmented acquisition requires a number of breath-holds to image the heart. Single-shot phase-sensitive inversion-recovery (PSIR) true-FISP may be combined with parallel imaging using SENSE to achieve high spatial resolution. SNR may be improved by averaging multiple motion-corrected images acquired during free breathing. PSIR techniques have demonstrated a number of benefits including consistent contrast and appearance over a relatively wide range of inversion recovery times (TI), improved contrast-to-noise ratio, and consistent size of the enhanced region. Comparison between images acquired using segmented breath-held turbo-FLASH and averaged, motion-corrected, free-breathing true-FISP show excellent agreement of measured CNR and infarct size. In this study, motion correction was implemented using image registration postprocessing rather than navigator correction of individual frames. Navigator techniques may be incorporated as well.

Original languageEnglish (US)
Pages (from-to)194-200
Number of pages7
JournalMagnetic resonance in medicine
Volume53
Issue number1
DOIs
StatePublished - Jan 2005

Keywords

  • Delayed enhancement
  • Free-breathing
  • Heart
  • MRI
  • Motion correction
  • Myocardial infarction
  • Parallel MRI
  • Phase sensitive
  • SENSE

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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    Kellman, P., Larson, A. C., Hsu, L. Y., Chung, Y. C., Simonetti, O. P., McVeigh, E. R., & Arai, A. E. (2005). Motion-corrected free-breathing delayed enhancement imaging of myocardial infarction. Magnetic resonance in medicine, 53(1), 194-200. https://doi.org/10.1002/mrm.20333