Motor slowing in asymptomatic HIV infection.

M. L. Fitzgibbon*, David Cella, G. Humfleet, E. Griffin, K. Sheridan

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

14 Scopus citations


To examine neuropsychological deficits associated with the human immunodeficiency virus (HIV), 25 asymptomatic homosexual men and sexual partners of intravenous drug users and 25 seronegative homosexual men and nonhigh-risk heterosexuals were assessed on measures of fine motor control, visual scanning, attention, depression, and global psychological functioning. Analysis suggested that HIV infection is associated with reduced fine motor control. Seropositivity is associated with elevated depression and global psychological maladjustment. When depression and global adjustment were analyzed as covariates, motor slowing was evident in the seropositive group. These findings suggest an association between motor slowing and HIV infection in asymptomatic subjects and point to the necessity of measuring affect at least as a control variable. Further study is needed to determine whether the fine motor deficit evident in this sample is limited to distinct subgrouping of the over-all sample.

Original languageEnglish (US)
Pages (from-to)1331-1338
Number of pages8
JournalPerceptual and Motor Skills
Issue number3 Pt 2
StatePublished - Jun 1 1989

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Sensory Systems


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