MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study

Pankaj Kulkarni; Sakura Sikander; Heather Cornnell; Jeremy Burt; Sumit Laha; Pradipta Biswas; Ulas Bagci; Sang Eun Song

doi:10.1115/DMD2019-3281

MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study

Pankaj Kulkarni^*, Sakura Sikander, Heather Cornnell, Jeremy Burt, Sumit Laha, Pradipta Biswas, Ulas Bagci, Sang Eun Song

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

Most of the existing MRI guided robotic needle guide systems have been limited to research purposes and have not progressed towards clinical applications due to complex and bulky structures. The ‘device-to-image’ registration step further complicates the operation and significantly increases the overall procedure time. To address limitations, we developed an MRI guided transperineal prostate biopsy guide system that uses the concept of a ‘fixed coordinate device’ to simplify the overall biopsy procedure and eliminate the registration step, making the procedure more clinically friendly. We performed proof-of-concept targeting experiments using an agar phantom under 3T MRI. The targeting results were analyzed, and initial results prove that the simplified intervention concept would well be feasible. We plan to extend the study further to identify error components.

Original language	English (US)
Title of host publication	Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019
Publisher	American Society of Mechanical Engineers (ASME)
ISBN (Electronic)	9780791841037
DOIs	https://doi.org/10.1115/DMD2019-3281
State	Published - 2019
Externally published	Yes
Event	2019 Design of Medical Devices Conference, DMD 2019 - Minneapolis, United States Duration: Apr 15 2019 → Apr 18 2019

Publication series

Name	Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019

Conference

Conference	2019 Design of Medical Devices Conference, DMD 2019
Country/Territory	United States
City	Minneapolis
Period	4/15/19 → 4/18/19

Keywords

MRI
Needle guide
Prostate biopsy

ASJC Scopus subject areas

Biomedical Engineering

Access to Document

10.1115/DMD2019-3281

Cite this

Kulkarni, P., Sikander, S., Cornnell, H., Burt, J., Laha, S., Biswas, P., Bagci, U., & Song, S. E. (2019). MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study. In Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019 (Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/DMD2019-3281

Kulkarni, Pankaj ; Sikander, Sakura ; Cornnell, Heather et al. / MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide : Initial feasibility study. Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019. American Society of Mechanical Engineers (ASME), 2019. (Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019).

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title = "MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study",

abstract = "Most of the existing MRI guided robotic needle guide systems have been limited to research purposes and have not progressed towards clinical applications due to complex and bulky structures. The {\textquoteleft}device-to-image{\textquoteright} registration step further complicates the operation and significantly increases the overall procedure time. To address limitations, we developed an MRI guided transperineal prostate biopsy guide system that uses the concept of a {\textquoteleft}fixed coordinate device{\textquoteright} to simplify the overall biopsy procedure and eliminate the registration step, making the procedure more clinically friendly. We performed proof-of-concept targeting experiments using an agar phantom under 3T MRI. The targeting results were analyzed, and initial results prove that the simplified intervention concept would well be feasible. We plan to extend the study further to identify error components.",

keywords = "MRI, Needle guide, Prostate biopsy",

author = "Pankaj Kulkarni and Sakura Sikander and Heather Cornnell and Jeremy Burt and Sumit Laha and Pradipta Biswas and Ulas Bagci and Song, {Sang Eun}",

note = "Funding Information: The work is supported by Central Florida Health Research. We thank Timothy Linder, Lab Manager at the Manufacturing Lab at the University of Central Florida for assistance with device manufacturing. Publisher Copyright: Copyright {\textcopyright} 2019 ASME; 2019 Design of Medical Devices Conference, DMD 2019 ; Conference date: 15-04-2019 Through 18-04-2019",

year = "2019",

doi = "10.1115/DMD2019-3281",

language = "English (US)",

series = "Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019",

publisher = "American Society of Mechanical Engineers (ASME)",

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Kulkarni, P, Sikander, S, Cornnell, H, Burt, J, Laha, S, Biswas, P, Bagci, U & Song, SE 2019, MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study. in Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019. Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019, American Society of Mechanical Engineers (ASME), 2019 Design of Medical Devices Conference, DMD 2019, Minneapolis, United States, 4/15/19. https://doi.org/10.1115/DMD2019-3281

MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study. / Kulkarni, Pankaj; Sikander, Sakura; Cornnell, Heather et al.
Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019. American Society of Mechanical Engineers (ASME), 2019. (Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AU - Kulkarni, Pankaj

AU - Sikander, Sakura

AU - Cornnell, Heather

AU - Burt, Jeremy

AU - Laha, Sumit

AU - Biswas, Pradipta

AU - Bagci, Ulas

AU - Song, Sang Eun

N1 - Funding Information: The work is supported by Central Florida Health Research. We thank Timothy Linder, Lab Manager at the Manufacturing Lab at the University of Central Florida for assistance with device manufacturing. Publisher Copyright: Copyright © 2019 ASME

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N2 - Most of the existing MRI guided robotic needle guide systems have been limited to research purposes and have not progressed towards clinical applications due to complex and bulky structures. The ‘device-to-image’ registration step further complicates the operation and significantly increases the overall procedure time. To address limitations, we developed an MRI guided transperineal prostate biopsy guide system that uses the concept of a ‘fixed coordinate device’ to simplify the overall biopsy procedure and eliminate the registration step, making the procedure more clinically friendly. We performed proof-of-concept targeting experiments using an agar phantom under 3T MRI. The targeting results were analyzed, and initial results prove that the simplified intervention concept would well be feasible. We plan to extend the study further to identify error components.

AB - Most of the existing MRI guided robotic needle guide systems have been limited to research purposes and have not progressed towards clinical applications due to complex and bulky structures. The ‘device-to-image’ registration step further complicates the operation and significantly increases the overall procedure time. To address limitations, we developed an MRI guided transperineal prostate biopsy guide system that uses the concept of a ‘fixed coordinate device’ to simplify the overall biopsy procedure and eliminate the registration step, making the procedure more clinically friendly. We performed proof-of-concept targeting experiments using an agar phantom under 3T MRI. The targeting results were analyzed, and initial results prove that the simplified intervention concept would well be feasible. We plan to extend the study further to identify error components.

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Kulkarni P, Sikander S, Cornnell H, Burt J, Laha S, Biswas P et al. MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study. In Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019. American Society of Mechanical Engineers (ASME). 2019. (Frontiers in Biomedical Devices, BIOMED - 2019 Design of Medical Devices Conference, DMD 2019). doi: 10.1115/DMD2019-3281

MRI-guided, transperineal prostate biopsy using fixed coordinate needle guide: Initial feasibility study

Abstract

Publication series

Conference

Keywords

ASJC Scopus subject areas

Access to Document

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