Multidrug-resistant gram-negative infections cause significant mortality and morbidity in the transplant and oncology patient population. Prolonged hospitalization and prior exposure to broad-spectrum antibiotics are common risk factors. Prevention strategies include daily bathing with chlorhexidine gluconate and use of isolation precautions. Recent data suggest that carbapenems provide adequate empiric therapy for most patients. However, culture data should be closely monitored to avoid overuse of broad-spectrum therapy.
|Original language||English (US)|
|Title of host publication||Pediatric Transplant and Oncology Infectious Diseases|
|State||Published - Jan 1 2020|
ASJC Scopus subject areas