Multifunctional nano-bio materials within cellular machinery

Functional nanoscale materials that possess specific physical or chemical properties can leverage energy transduction in vivo. Once these materials integrate with biomolecules they combine physical properties of inorganic material and the biorecognition capabilities of bio-organic moieties. Such nanobio hybrids can be interfaced with living cells, the elementary functional units of life. These nanobio systems are capable of bio-manipulation or actuation via altering intracellular biochemical pathways. Thus, nanobio conjugates are appealing for a wide range of applications from the life sciences and nanomedicine to catalysis and clean energy production. Here we highlight recent progress in our efforts to develop smart nanobio hybrid materials, and to study their performance within cellular machinery under application of external stimuli, such as light or magnetic fields.