Multimodal epidermal devices for hydration monitoring

Siddharth Krishnan, Yunzhou Shi, R. Chad Webb, Yinji Ma, Philippe Bastien, Kaitlyn E. Crawford, Ao Wang, Xue Feng, Megan Manco, Jonas Kurniawan, Edward Tir, Yonggang Huang, Guive Balooch, Rafal M. Pielak*, John A. Rogers

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

45 Scopus citations


Precise, quantitative in vivo monitoring of hydration levels in the near surface regions of the skin can be useful in preventing skin-based pathologies, and regulating external appearance. Here we introduce multimodal sensors with important capabilities in this context, rendered in soft, ultrathin, ‘skin-like’ formats with numerous advantages over alternative technologies, including the ability to establish intimate, conformal contact without applied pressure, and to provide spatiotemporally resolved data on both electrical and thermal transport properties from sensitive regions of the skin. Systematic in vitro studies and computational models establish the underlying measurement principles and associated approaches for determination of temperature, thermal conductivity, thermal diffusivity, volumetric heat capacity, and electrical impedance using simple analysis algorithms. Clinical studies on 20 patients subjected to a variety of external stimuli validate the device operation and allow quantitative comparisons of measurement capabilities to those of existing state-of-the-art tools.

Original languageEnglish (US)
Article number17014
JournalMicrosystems and Nanoengineering
StatePublished - 2017


  • Epidermal electronics
  • Hydration monitoring
  • Thermal characterization

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics
  • Materials Science (miscellaneous)
  • Condensed Matter Physics
  • Industrial and Manufacturing Engineering
  • Electrical and Electronic Engineering


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