Multiple roles for Wnt signaling in the development of the vertebrate neural crest

Elizabeth Heeg-Truesdell*, Carole LaBonne

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

2 Scopus citations

Abstract

The neural crest is a cell type unique to vertebrates that gives rise to a diverse set of derivatives essential to the vertebrate body plan. The formation and subsequent diversification of neural crest cells is a complex multistep process dependent on the reiterative use of multiple intracellular-signaling pathways. Notable among these is the Wnt-signaling pathway, which plays prominent roles at multiple stages of neural crest development.

Original languageEnglish (US)
Title of host publicationWnt Signaling in Embryonic Development
EditorsSergei Sokol
Pages203-221
Number of pages19
DOIs
StatePublished - 2007

Publication series

NameAdvances in Developmental Biology
Volume17
ISSN (Print)1574-3349

Funding

The authors gratefully acknowledge members of the laboratory for valuable discussions. EH‐T was supported by the Cellular and Molecular Basis of Disease training program (NIGMS). CL is a Scholar of the GM Cancer Research Foundation. Work in our laboratory referenced within was supported by grants from the American Cancer Society and the NIH to CL.

ASJC Scopus subject areas

  • Biochemistry
  • Developmental Biology

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