Multiplexed DNA detection with biobarcoded nanoparticle probes

Savka I. Stoeva*, Jae Seung Lee, C. Shad Thaxton, Chad A. Mirkin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

223 Scopus citations

Abstract

(Figure Presented) Sorting the mail: A highly selective assay for the detection of multiple DNA targets in solution was developed based on gold nanoparticles with oligonucleotide reporters. Four DNA targets associated with infectious viruses were detected simultaneously without enzymatic amplification at mid-femtomolar concentrations.

Original languageEnglish (US)
Pages (from-to)3303-3306
Number of pages4
JournalAngewandte Chemie - International Edition
Volume45
Issue number20
DOIs
StatePublished - May 12 2006

Keywords

  • Barcodes
  • Biosensors
  • DNA detection
  • Gold
  • Nanoparticles

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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