Multiplexed protein arrays enabled by polymer pen lithography: Addressing the inking challenge

Zijian Zheng*, Weston L. Daniel, Louise R. Giam, Fengwei Huo, Andrew J. Senesi, Gengfeng Zheng, Chad A. Mirkin

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

101 Scopus citations

Abstract

High-end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nanoand microscale protein features per second (see picture). It is a general approach, which in principle can be extended to any substance that can be transported by PPL.

Original languageEnglish (US)
Pages (from-to)7626-7629
Number of pages4
JournalAngewandte Chemie - International Edition
Volume48
Issue number41
DOIs
StatePublished - Sep 28 2009

Keywords

  • Inks
  • Multiplex techniques
  • Patterning
  • Polymer pen lithography
  • Protein arrays

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)

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