Multiplexed protein arrays enabled by polymer pen lithography: Addressing the inking challenge

Zijian Zheng; Weston L. Daniel; Louise R. Giam; Fengwei Huo; Andrew J. Senesi; Gengfeng Zheng; Chad A. Mirkin

doi:10.1002/anie.200902649

Multiplexed protein arrays enabled by polymer pen lithography: Addressing the inking challenge

Zijian Zheng^*, Weston L. Daniel, Louise R. Giam, Fengwei Huo, Andrew J. Senesi, Gengfeng Zheng, Chad A. Mirkin

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

101 Scopus citations

Abstract

High-end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nanoand microscale protein features per second (see picture). It is a general approach, which in principle can be extended to any substance that can be transported by PPL.

Original language	English (US)
Pages (from-to)	7626-7629
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	48
Issue number	41
DOIs	https://doi.org/10.1002/anie.200902649
State	Published - Sep 28 2009

Keywords

Inks
Multiplex techniques
Patterning
Polymer pen lithography
Protein arrays

ASJC Scopus subject areas

Catalysis
Chemistry(all)

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10.1002/anie.200902649

Cite this

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abstract = "High-end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nanoand microscale protein features per second (see picture). It is a general approach, which in principle can be extended to any substance that can be transported by PPL.",

keywords = "Inks, Multiplex techniques, Patterning, Polymer pen lithography, Protein arrays",

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AU - Daniel, Weston L.

AU - Giam, Louise R.

AU - Huo, Fengwei

AU - Senesi, Andrew J.

AU - Zheng, Gengfeng

AU - Mirkin, Chad A.

PY - 2009/9/28

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AB - High-end printer: A novel way of using a polymer pen lithography (PPL) array mould to localize different inks on the pens of a PPL array has been developed. This technique allows for rapid pen inking and subsequent generation of multiplexed patterns of up to 150 000 nanoand microscale protein features per second (see picture). It is a general approach, which in principle can be extended to any substance that can be transported by PPL.

KW - Inks

KW - Multiplex techniques

KW - Patterning

KW - Polymer pen lithography

KW - Protein arrays

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Multiplexed protein arrays enabled by polymer pen lithography: Addressing the inking challenge

Abstract

Keywords

ASJC Scopus subject areas

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