Multisystem Inflammatory Syndrome in Children and Cardiac Involvement: A Quaternary Center Experience

Diego Cruz Vidal*, Simon Lee, Stacy P. Ardoin, Djhenne Dalmacy, Juan Chaparro, Cristin Blaney, Vilmarie Rodriguez, Amanda Sankar, Shoghik Akoghlanian, Richard Lisciandro, Matthew Washam, Roshini S. Abraham, Amy Leber, Meika Eby, Berkeley Bennett, Guliz Erdem*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

We prospectively analyzed clinical and laboratory characteristics associated with cardiac involvement and severe presentation in multisystem inflammatory syndrome in children. Of 146 patients, 66 (45.2%) had cardiac dysfunction and 26 (17.8%) had coronary artery abnormalities. Lower serum albumin levels, absolute lymphocyte and platelet counts, and elevated ferritin, fibrinogen, d-dimer and interleukin-6 levels were associated with cardiac dysfunction. Possible treatment complications were identified.

Original languageEnglish (US)
Pages (from-to)E160-E163
JournalPediatric Infectious Disease Journal
Volume43
Issue number5
DOIs
StatePublished - May 1 2024

Keywords

  • COVID-19
  • MIS-C
  • cardiac involvement
  • outcomes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Microbiology (medical)
  • Infectious Diseases

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