Musculoskeletal involvement of COVID-19: review of imaging

Santhoshini Leela Ramani, Jonathan Samet, Colin K. Franz, Christine Hsieh, Cuong V. Nguyen, Craig Horbinski, Swati Deshmukh*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

72 Scopus citations


The global pandemic of coronavirus disease 2019 (COVID-19) has revealed a surprising number of extra-pulmonary manifestations of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. While myalgia is a common clinical feature of COVID-19, other musculoskeletal manifestations of COVID-19 were infrequently described early during the pandemic. There have been emerging reports, however, of an array of neuromuscular and rheumatologic complications related to COVID-19 infection and disease course including myositis, neuropathy, arthropathy, and soft tissue abnormalities. Multimodality imaging supports diagnosis and evaluation of musculoskeletal disorders in COVID-19 patients. This article aims to provide a first comprehensive summary of musculoskeletal manifestations of COVID-19 with review of imaging.

Original languageEnglish (US)
Pages (from-to)1763-1773
Number of pages11
JournalSkeletal Radiology
Issue number9
StatePublished - Sep 2021


  • COVID-19
  • MR
  • Musculoskeletal
  • Neuromuscular
  • SARS-CoV-2
  • Ultrasound

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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