Mutant RUNX1 and histone tales

Lucy A. Godley*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

Abstract

In this issue of Blood, Lehnertz et al identify rare cases of histone H3 mutations at position K27 that alter methylation levels and cooperate with RUNX1 mutations,1 further strengthening the association between RUNX1 and polycomb repressive complex 2 (PRC2) activity in leukemic transformation.

Original languageEnglish (US)
Pages (from-to)2156-2157
Number of pages2
JournalBlood
Volume130
Issue number20
DOIs
StatePublished - Nov 16 2017

ASJC Scopus subject areas

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology

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