Mutations in PRPF31 inhibit pre-mRNA splicing of rhodopsin gene and cause apoptosis of retinal cells

Biochemistry, Genetics and Molecular Biology

• Nested Gene 100%
• PRPF31 100%
• Rhodopsin 70%
• Mutation 40%
• RNA Splicing 40%
• Apoptosis 20%
• Autosomal Dominant Inheritance 20%
• Retinitis pigmentosa 20%
• Mutant 20%
• Immunoprecipitation 10%
• Splicing Factor 10%
• Cell Death 10%
• Cell Culture 10%
• Intron 10%
• Photoreceptor Cell 10%
• Species 10%

INIS

• genes 100%
• rhodopsin 70%
• splicing 60%
• mutations 40%
• messenger-rna 40%
• apoptosis 30%
• proteins 20%
• mutants 20%
• humans 10%
• patients 10%
• in vitro 10%
• rna 10%
• defects 10%
• antibodies 10%
• cell cultures 10%
• introns 10%

Neuroscience

• Gene 100%
• PRPF31 100%
• Rhodopsin 70%
• Apoptosis 20%
• Retinitis pigmentosa 20%
• Protein 20%
• In Vitro 10%
• RNA 10%
• Antibodies 10%
• Cell Culture 10%
• Retinal Degeneration 10%
• Intron 10%
• Splicing Factor 10%
• Photoreceptor 10%