Myelin: Not just a conduit for conduction

Brian Popko

doi:10.1038/ng0303-327

Myelin: Not just a conduit for conduction

Brian Popko^*

^*Corresponding author for this work

Neurology

Research output: Contribution to journal › Short survey › peer-review

18 Scopus citations

Abstract

Most nerve axons of higher vertebrates are surrounded by a multilayered myelin membrane that is essential for promotion of rapid nerve conduction. A new study genetically uncouples the myelin-producing function of the myelinating cells from their role in axonal survival, suggesting that neurodegenerative disorders characterized by axonal loss might result from defects in the myelinating cells whether myelin irregularities are apparent or not.

Original language	English (US)
Pages (from-to)	327-328
Number of pages	2
Journal	Nature Genetics
Volume	33
Issue number	3
DOIs	https://doi.org/10.1038/ng0303-327
State	Published - Mar 1 2003

ASJC Scopus subject areas

Genetics

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abstract = "Most nerve axons of higher vertebrates are surrounded by a multilayered myelin membrane that is essential for promotion of rapid nerve conduction. A new study genetically uncouples the myelin-producing function of the myelinating cells from their role in axonal survival, suggesting that neurodegenerative disorders characterized by axonal loss might result from defects in the myelinating cells whether myelin irregularities are apparent or not.",

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AB - Most nerve axons of higher vertebrates are surrounded by a multilayered myelin membrane that is essential for promotion of rapid nerve conduction. A new study genetically uncouples the myelin-producing function of the myelinating cells from their role in axonal survival, suggesting that neurodegenerative disorders characterized by axonal loss might result from defects in the myelinating cells whether myelin irregularities are apparent or not.

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Myelin: Not just a conduit for conduction

Abstract

ASJC Scopus subject areas

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