Myocardial storage of chondroitin sulfate-containing moieties in Costello syndrome patients with severe hypertrophic cardiomyopathy

Keyphrases

• Hypertrophic Cardiomyopathy 100%
• Chondroitin Sulfate 100%
• Costello Syndrome 100%
• Cardiac Anomalies 28%
• Proteoglycan 28%
• Elastic Fibers 28%
• Postmortem Findings 28%
• Chondroitin-6-sulfate 28%
• Fibrosis 14%
• Cell Proliferation 14%
• Immunohistochemical Study 14%
• Malignancy 14%
• Intellectual Disability 14%
• Cardiomyocytes 14%
• Cardiac Hypertrophy 14%
• Developmental Delay 14%
• Soft Skin 14%
• Pathological Findings 14%
• Intracellular Accumulation 14%
• Sulfation 14%
• Tachycardia 14%
• Collagenous 14%
• Clinical Reports 14%
• Plantar 14%
• Histological Examination 14%
• Skeletal Abnormalities 14%
• Histochemical Study 14%
• Palmar 14%
• Normal Heart 14%
• Cardiovascular Malformations 14%
• Pericellular 14%
• Multiple Congenital Anomalies 14%
• Chondroitin 4-sulfate 14%
• Coarse Facial Features 14%

Biochemistry, Genetics and Molecular Biology

• Chondroitin Sulfate 100%
• Sulfate 60%
• Chondroitin 60%
• Cardiac Muscle Cell 40%
• Proteoglycan 40%
• Elastic Fiber 40%
• Sulfation 20%
• Cell Proliferation 20%
• Tachyarrhythmia 20%
• Tachycardia 20%