Myocardial Strain Measurement With 2-Dimensional Speckle-Tracking Echocardiography. Definition of Normal Range

Thomas H. Marwick*, Rodel L. Leano, Joseph Brown, Jing Ping Sun, Rainer Hoffmann, Peter Lysyansky, Michael Becker, James D. Thomas

*Corresponding author for this work

Research output: Contribution to journalArticle

355 Scopus citations

Abstract

The interpretation of wall motion is an important component of echocardiography but remains a source of variation between observers. It has been believed that automated quantification of left ventricular (LV) systolic function by measurement of LV systolic strain from speckle-tracking echocardiography might be helpful. This multicenter study of nearly 250 volunteers without evidence of cardiovascular disease showed an average LV peak systolic strain of -18.6 ± 0.1%. Although strain was influenced by weight, blood pressure, and heart rate, these features accounted for only 16% of variance. However, there was significant segmental variation of regional strain to necessitate the use of site-specific normal ranges.

Original languageEnglish (US)
Pages (from-to)80-84
Number of pages5
JournalJACC: Cardiovascular Imaging
Volume2
Issue number1
DOIs
StatePublished - Jan 2009

Keywords

  • regional left ventricular function
  • speckle tracking
  • strain

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Cardiology and Cardiovascular Medicine

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