Nanoparticle Superlattices through Template-Encoded DNA Dendrimers

Ho Fung Cheng, Max E. Distler, Byeongdu Lee, Wenjie Zhou, Steven Weigand, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

3 Scopus citations

Abstract

The chemical interactions that lead to the emergence of hierarchical structures are often highly complex and difficult to program. Herein, the synthesis of a series of superlattices based upon 30 different structurally reconfigurable DNA dendrimers is reported, each of which presents a well-defined number of single-stranded oligonucleotides (i.e., sticky ends) on its surface. Such building blocks assemble with complementary DNA-functionalized gold nanoparticles (AuNPs) to yield five distinct crystal structures, depending upon choice of dendrimer and defined by phase symmetry. These DNA dendrimers can associate to form micelle-dendrimers, whereby the extent of association can be modulated based upon surfactant concentration and dendrimer length to produce a low-symmetry Ti5Ga4-type phase that has yet to be reported in the field of colloidal crystal engineering. Taken together, colloidal crystals that feature three different types of particle bonding interactions - template-dendron, dendrimer-dendrimer, and DNA-modified AuNP-dendrimer - are reported, illustrating how sequence-defined recognition and dynamic association can be combined to yield complex hierarchical materials.

Original languageEnglish (US)
Pages (from-to)17170-17179
Number of pages10
JournalJournal of the American Chemical Society
Volume143
Issue number41
DOIs
StatePublished - Oct 20 2021

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

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