Nanoreactors for studying single nanoparticle coarsening

Jinan Chai, Xing Liao, Louise R. Giam, Chad A. Mirkin*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

34 Scopus citations


The ability to observe intermediate structures as part of coarsening processes that lead to the formation of single nanoparticles (NPs) is important in gaining fundamental insight pertaining to nanostructure growth. Here, we use scanning probe block copolymer lithography (SPBCL) to create "nanoreactors" having attoliter volumes, which confine Au NP nucleation and growth to features having diameters <150 nm on a substrate. With this technique, one can use in situ TEM to directly observe and study NP coarsening and differentiate Ostwald ripening from coalescence processes. Importantly, the number of metal atoms that can engage in coarsening can be controlled with this technique, and TEM "snapshots" of particle growth can be taken. The size of the resulting nanostructures can be controlled in the 2-10 nm regime.

Original languageEnglish (US)
Pages (from-to)158-161
Number of pages4
JournalJournal of the American Chemical Society
Issue number1
StatePublished - Jan 11 2012

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry


Dive into the research topics of 'Nanoreactors for studying single nanoparticle coarsening'. Together they form a unique fingerprint.

Cite this