Na+,K+‐ATPase and Mg2+‐ATPase Activities in Different Regions of Rat Brain During Alloxan Diabetes

C. S K Mayanil, S. M I Kazmi, N. Z. Baquer*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

33 Scopus citations


Abstract: The effect of alloxan diabetes on the activities of Na+,K+‐ATPase and Mg2+‐ATPase was studied in three regions of rat brain at various time intervals after the onset of diabetes. It was observed that Na2+,K2+‐ATPase activity increased at early time intervals after diabetes, followed by a recovery to near control levels in all three regions of the brain. There was an overall increase in Mg2+‐ATPase activity in all the regions. A reversal of the effect was observed with insulin administration to the diabetic rats

Original languageEnglish (US)
Pages (from-to)903-908
Number of pages6
JournalJournal of Neurochemistry
Issue number4
StatePublished - Jan 1 1982


  • ATPase
  • ATPase‐Mg
  • Brain
  • Diabetes
  • Dopamine
  • Insulin
  • Na,K
  • Norepinephrine

ASJC Scopus subject areas

  • Biochemistry
  • Cellular and Molecular Neuroscience

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