National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development

Pushpa V. Thadani; Jerome F. Strauss; Sudhansu K. Dey; Virginia M. Anderson; Kenneth L. Audus; Karen S. Coats; James C. Cross; Adrian Erlebacher; Vadivel Ganapathy; Daniel I. Linzer; Richard K. Miller; Donald A. Novak; Rao S. Rapaka; Yoel Sadovsky; Carolyn M. Salafia; Michael Soares; Jashvant Unadkat

doi:10.1016/j.ajog.2004.07.059

National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development

Pushpa V. Thadani, Jerome F. Strauss, Sudhansu K. Dey, Virginia M. Anderson, Kenneth L. Audus, Karen S. Coats, James C. Cross, Adrian Erlebacher, Vadivel Ganapathy, Daniel I. Linzer, Richard K. Miller, Donald A. Novak, Rao S. Rapaka, Yoel Sadovsky, Carolyn M. Salafia, Michael Soares, Jashvant Unadkat

Molecular Biosciences

Research output: Contribution to journal › Article › peer-review

16 Scopus citations

Abstract

The use of illicit and licit drugs during pregnancy is a major public health concern because of potential adverse effects on the fetus and the risk to maternal health. Because the placenta is the primary link between the mother and the conceptus and is essential for the growth and survival of the fetus, abnormalities in placental formation and function resulting from drug use could have a major influence on pregnancy outcome. At present, little information is available on the impact of abused drugs on placental biology alone or in combination with other "host" factors (eg, stress, infections). This prompted the National Institute on Drug Abuse (NIDA) to convene a meeting of experts in placental biology to review cutting-edge research with the mission to translate existing information to new clinical and research initiatives in the drug abuse field. This report summarizes the presentations and research recommendations resulting from the workshop discussions.

Original language	English (US)
Pages (from-to)	1858-1862
Number of pages	5
Journal	American journal of obstetrics and gynecology
Volume	191
Issue number	6
DOIs	https://doi.org/10.1016/j.ajog.2004.07.059
State	Published - Dec 2004

Keywords

Drugs of abuse
Fetal growth
Placenta
Proteins
Transporters

ASJC Scopus subject areas

Obstetrics and Gynecology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.ajog.2004.07.059

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Thadani, P. V., Strauss, J. F., Dey, S. K., Anderson, V. M., Audus, K. L., Coats, K. S., Cross, J. C., Erlebacher, A., Ganapathy, V., Linzer, D. I., Miller, R. K., Novak, D. A., Rapaka, R. S., Sadovsky, Y., Salafia, C. M., Soares, M., & Unadkat, J. (2004). National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development. American journal of obstetrics and gynecology, 191(6), 1858-1862. https://doi.org/10.1016/j.ajog.2004.07.059

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abstract = "The use of illicit and licit drugs during pregnancy is a major public health concern because of potential adverse effects on the fetus and the risk to maternal health. Because the placenta is the primary link between the mother and the conceptus and is essential for the growth and survival of the fetus, abnormalities in placental formation and function resulting from drug use could have a major influence on pregnancy outcome. At present, little information is available on the impact of abused drugs on placental biology alone or in combination with other {"}host{"} factors (eg, stress, infections). This prompted the National Institute on Drug Abuse (NIDA) to convene a meeting of experts in placental biology to review cutting-edge research with the mission to translate existing information to new clinical and research initiatives in the drug abuse field. This report summarizes the presentations and research recommendations resulting from the workshop discussions.",

keywords = "Drugs of abuse, Fetal growth, Placenta, Proteins, Transporters",

author = "Thadani, {Pushpa V.} and Strauss, {Jerome F.} and Dey, {Sudhansu K.} and Anderson, {Virginia M.} and Audus, {Kenneth L.} and Coats, {Karen S.} and Cross, {James C.} and Adrian Erlebacher and Vadivel Ganapathy and Linzer, {Daniel I.} and Miller, {Richard K.} and Novak, {Donald A.} and Rapaka, {Rao S.} and Yoel Sadovsky and Salafia, {Carolyn M.} and Michael Soares and Jashvant Unadkat",

year = "2004",

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doi = "10.1016/j.ajog.2004.07.059",

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Thadani, PV, Strauss, JF, Dey, SK, Anderson, VM, Audus, KL, Coats, KS, Cross, JC, Erlebacher, A, Ganapathy, V, Linzer, DI, Miller, RK, Novak, DA, Rapaka, RS, Sadovsky, Y, Salafia, CM, Soares, M & Unadkat, J 2004, 'National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development', American journal of obstetrics and gynecology, vol. 191, no. 6, pp. 1858-1862. https://doi.org/10.1016/j.ajog.2004.07.059

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AU - Thadani, Pushpa V.

AU - Strauss, Jerome F.

AU - Dey, Sudhansu K.

AU - Anderson, Virginia M.

AU - Audus, Kenneth L.

AU - Coats, Karen S.

AU - Cross, James C.

AU - Erlebacher, Adrian

AU - Ganapathy, Vadivel

AU - Linzer, Daniel I.

AU - Miller, Richard K.

AU - Novak, Donald A.

AU - Rapaka, Rao S.

AU - Sadovsky, Yoel

AU - Salafia, Carolyn M.

AU - Soares, Michael

AU - Unadkat, Jashvant

PY - 2004/12

Y1 - 2004/12

N2 - The use of illicit and licit drugs during pregnancy is a major public health concern because of potential adverse effects on the fetus and the risk to maternal health. Because the placenta is the primary link between the mother and the conceptus and is essential for the growth and survival of the fetus, abnormalities in placental formation and function resulting from drug use could have a major influence on pregnancy outcome. At present, little information is available on the impact of abused drugs on placental biology alone or in combination with other "host" factors (eg, stress, infections). This prompted the National Institute on Drug Abuse (NIDA) to convene a meeting of experts in placental biology to review cutting-edge research with the mission to translate existing information to new clinical and research initiatives in the drug abuse field. This report summarizes the presentations and research recommendations resulting from the workshop discussions.

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KW - Fetal growth

KW - Placenta

KW - Proteins

KW - Transporters

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National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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