National Institute on Drug Abuse Conference report on placental proteins, drug transport, and fetal development

Pushpa V. Thadani, Jerome F. Strauss, Sudhansu K. Dey, Virginia M. Anderson, Kenneth L. Audus, Karen S. Coats, James C. Cross, Adrian Erlebacher, Vadivel Ganapathy, Daniel I. Linzer, Richard K. Miller, Donald A. Novak, Rao S. Rapaka, Yoel Sadovsky, Carolyn M. Salafia, Michael Soares, Jashvant Unadkat

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

The use of illicit and licit drugs during pregnancy is a major public health concern because of potential adverse effects on the fetus and the risk to maternal health. Because the placenta is the primary link between the mother and the conceptus and is essential for the growth and survival of the fetus, abnormalities in placental formation and function resulting from drug use could have a major influence on pregnancy outcome. At present, little information is available on the impact of abused drugs on placental biology alone or in combination with other "host" factors (eg, stress, infections). This prompted the National Institute on Drug Abuse (NIDA) to convene a meeting of experts in placental biology to review cutting-edge research with the mission to translate existing information to new clinical and research initiatives in the drug abuse field. This report summarizes the presentations and research recommendations resulting from the workshop discussions.

Original languageEnglish (US)
Pages (from-to)1858-1862
Number of pages5
JournalAmerican journal of obstetrics and gynecology
Volume191
Issue number6
DOIs
StatePublished - Dec 2004

Keywords

  • Drugs of abuse
  • Fetal growth
  • Placenta
  • Proteins
  • Transporters

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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