Natural orifice translumenal endoscopic surgery: Progress in humans since white paper

Byron F. Santos, Eric S. Hungness

Research output: Contribution to journalArticlepeer-review

64 Scopus citations

Abstract

Since the first description of the concept of natural orifice translumenal endoscopic surgery (NOTES), a substantial number of clinical NOTES reports have appeared in the literature. This editorial reviews the available human data addressing research questions originally proposed by the white paper, including determining the optimal method of access for NOTES, developing safe methods of lumenal closure, suturing and anastomotic devices, advanced multitasking platforms, addressing the risk of infection, managing complications, addressing challenges with visualization, and training for NOTES procedures. An analysis of the literature reveals that so far transvaginal access and closure appear to be the most feasible techniques for NOTES, with a limited, but growing transgastric, transrectal, and transesophageal NOTES experience in humans. The theoretically increased risk of infection as a result of NOTES procedures has not been substantiated in transvaginal and transgastric procedures so far. Development of suturing and anastomotic devices and advanced platforms for NOTES has progressed slowly, with limited clinical data on their use so far. Data on the optimal management and incidence of intraoperative complications remain sparse, although possible factors contributing to complications are discussed. Finally, this editorial discusses the likely direction of future NOTES development and its possible role in clinical practice.

Original languageEnglish (US)
Pages (from-to)1655-1665
Number of pages11
JournalWorld Journal of Gastroenterology
Volume17
Issue number13
DOIs
StatePublished - Apr 7 2011

Keywords

  • Complications
  • Endoscopic
  • Natural orifice translumenal endoscopic surgery
  • Outcomes
  • Surgery

ASJC Scopus subject areas

  • Gastroenterology

Fingerprint

Dive into the research topics of 'Natural orifice translumenal endoscopic surgery: Progress in humans since white paper'. Together they form a unique fingerprint.

Cite this