NCCN Practice Guidelines for Colorectal Cancer.

Al B Benson III, M. A. Choti, A. M. Cohen, J. H. Doroshow, C. Fuchs, K. Kiel, E. W. Martin, C. McGinn, N. J. Petrelli, J. A. Posey, J. M. Skibber, A. Venook, T. J. Yeatman

Research output: Contribution to journalArticle

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Abstract

The NCCN Colorectal Cancer Guidelines panel believes that a multidisciplinary approach is necessary for the management of the patient with colorectal cancer. The panel endorses the concept that treatment of patients in a clinical trial has priority over standard or accepted therapy. The recommended surgical procedure for resectable colon cancer is an en bloc resection; laparoscopic surgery should be done only in the context of a clinical trial. For patients with stage III disease, 5-FU-based adjuvant therapy is recommended. A patient who has metastatic disease in the liver or lung should be considered for surgical resection if he or she is a candidate for surgery and if surgery can extend survival. Surgery should be followed by adjuvant chemotherapy. The panel advocates a conservative post-treatment surveillance program for colon and rectal carcinoma patients. Serial CEA determinations are appropriate if the patient is a candidate for aggressive surgical resection, should recurrence be detected. Abdominal and pelvic CT scans should be utilized only when there are clinical indications of possible recurrence. Patients whose disease progresses during 5-FU-based therapy should be treated with irinotecan or encouraged to participate in a phase I or phase II clinical trial.

Original languageEnglish (US)
Pages (from-to)203-212
Number of pages10
JournalOncology (Williston Park, N.Y.)
Volume14
Issue number11 A
StatePublished - Jan 1 2000

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Practice Guidelines
Colorectal Neoplasms
irinotecan
Fluorouracil
Clinical Trials
Recurrence
Phase II Clinical Trials
Therapeutics
Adjuvant Chemotherapy
Laparoscopy
Colonic Neoplasms
Lung Diseases
Liver Diseases
Colon
Guidelines
Carcinoma
Survival

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Cite this

Benson III, A. B., Choti, M. A., Cohen, A. M., Doroshow, J. H., Fuchs, C., Kiel, K., ... Yeatman, T. J. (2000). NCCN Practice Guidelines for Colorectal Cancer. Oncology (Williston Park, N.Y.), 14(11 A), 203-212.
Benson III, Al B ; Choti, M. A. ; Cohen, A. M. ; Doroshow, J. H. ; Fuchs, C. ; Kiel, K. ; Martin, E. W. ; McGinn, C. ; Petrelli, N. J. ; Posey, J. A. ; Skibber, J. M. ; Venook, A. ; Yeatman, T. J. / NCCN Practice Guidelines for Colorectal Cancer. In: Oncology (Williston Park, N.Y.). 2000 ; Vol. 14, No. 11 A. pp. 203-212.
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Benson III, AB, Choti, MA, Cohen, AM, Doroshow, JH, Fuchs, C, Kiel, K, Martin, EW, McGinn, C, Petrelli, NJ, Posey, JA, Skibber, JM, Venook, A & Yeatman, TJ 2000, 'NCCN Practice Guidelines for Colorectal Cancer.', Oncology (Williston Park, N.Y.), vol. 14, no. 11 A, pp. 203-212.

NCCN Practice Guidelines for Colorectal Cancer. / Benson III, Al B; Choti, M. A.; Cohen, A. M.; Doroshow, J. H.; Fuchs, C.; Kiel, K.; Martin, E. W.; McGinn, C.; Petrelli, N. J.; Posey, J. A.; Skibber, J. M.; Venook, A.; Yeatman, T. J.

In: Oncology (Williston Park, N.Y.), Vol. 14, No. 11 A, 01.01.2000, p. 203-212.

Research output: Contribution to journalArticle

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Benson III AB, Choti MA, Cohen AM, Doroshow JH, Fuchs C, Kiel K et al. NCCN Practice Guidelines for Colorectal Cancer. Oncology (Williston Park, N.Y.). 2000 Jan 1;14(11 A):203-212.