Near-infrared light photoacoustic ophthalmoscopy

Tan Liu; Qing Wei; Wei Song; Janice M. Burke; Shuliang Jiao; Hao F. Zhang

doi:10.1364/BOE.3.000792

Near-infrared light photoacoustic ophthalmoscopy

Tan Liu, Qing Wei, Wei Song, Janice M. Burke, Shuliang Jiao, Hao F. Zhang

Biomedical Engineering

Research output: Contribution to journal › Article › peer-review

26 Scopus citations

Abstract

We achieved photoacoustic ophthalmoscopy (PAOM) imaging of the retina with near-infrared (NIR) light illumination. A PAOM imaging system with dual-wavelength illumination at 1064 nm and 532 nm was built. We compared in vivo imaging results of both albino and pigmented rat eyes at the two wavelengths. The results show that the bulk optical absorption of the retinal pigment epithelium (RPE) is only slightly higher than that of the retinal vessels at 532 nm while it becomes more than an order of magnitude higher than that of the retinal vessels at 1064 nm. These studies suggest that although visible light illumination is suitable for imaging both the retinal vessels and the RPE, NIR light illumination, being more comfortable to the eye, is better suited for RPE melanin related investigations and diagnoses.

Original language	English (US)
Pages (from-to)	792-799
Number of pages	8
Journal	Biomedical Optics Express
Volume	3
Issue number	4
DOIs	https://doi.org/10.1364/BOE.3.000792
State	Published - Apr 1 2012

ASJC Scopus subject areas

Biotechnology
Atomic and Molecular Physics, and Optics

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AU - Wei, Qing

AU - Song, Wei

AU - Burke, Janice M.

AU - Jiao, Shuliang

AU - Zhang, Hao F.

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Near-infrared light photoacoustic ophthalmoscopy

Abstract

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