Near-Infrared Spectroscopy: Clinical Use in High-Risk Neonates

Nhu N. Tran*, Michelle Tran, Jeraldine Lopez, Maxine Ogbaa, Jodie K. Votava-Smith, Ken M. Brady

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

2 Scopus citations


In this review, we describe the near-infrared spectroscopy (NIRS) technology and its clinical use in high-risk neonates in critical care settings. We searched databases (e.g., PubMed, Google Scholar, EBSCOhost) to find studies describing the use of NIRS on critically ill and high-risk neonates. Near-infrared spectroscopy provides continuous noninvasive monitoring of venous oxygen saturation. It uses technology similar to pulse oximetry to measure the oxygen saturation of hemoglobin in a tissue bed to describe the relative delivery and extraction of oxygen. Near-infrared spectroscopy can be a valuable bedside tool to provide clinicians indirect evidence of perfusion. It may prompt early interventions that promote oxygen delivery, which can improve high-risk neonatal outcomes.

Original languageEnglish (US)
Pages (from-to)73-79
Number of pages7
JournalNeonatal network : NN
Issue number2
StatePublished - 2021


  • NIRS
  • critically ill
  • high-risk
  • near-infrared spectroscopy
  • neonate

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care
  • Critical Care and Intensive Care Medicine


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