Needs and opportunities for research in hypersensitivity pneumonitis

Jordan N. Fink; Hector G. Ortega; Herbert Y. Reynolds; Yvon F. Cormier; Leland L. Fan; Terl J. Franks; Kathleen Kreiss; Steven Kunkel; David Lynch; Santiago Quirce; Cecile Rose; Robert P. Schleimer; Mark R. Schuyler; Moises Selman; Douglas Trout; Yasuyuki Yoshizawa

doi:10.1164/rccm.200409-1205WS

Needs and opportunities for research in hypersensitivity pneumonitis

Jordan N. Fink, Hector G. Ortega, Herbert Y. Reynolds^*, Yvon F. Cormier, Leland L. Fan, Terl J. Franks, Kathleen Kreiss, Steven Kunkel, David Lynch, Santiago Quirce, Cecile Rose, Robert P. Schleimer, Mark R. Schuyler, Moises Selman, Douglas Trout, Yasuyuki Yoshizawa

^*Corresponding author for this work

Medicine, Allergy Division

Research output: Contribution to journal › Review article › peer-review

171 Scopus citations

Abstract

Hypersensitivity pneumonitis (HP) develops after inhalation of many different environmental antigens, causing variable clinical symptoms that often make diagnosis uncertain. The prevalence of HP is higher than recognized, especially its chronic form. Mechanisms of disease are still incompletely known. Strategies to improve detection and diagnosis are needed, and treatment options, principally avoidance, are limited. A workshop recommended: a population-based study to more accurately document the incidence and prevalence of HP; better classification of disease stages, including natural history; evaluation of diagnostic tests and biomarkers used to detect disease; better correlation of computerized tomography lung imaging and pathologic changes; more study of inflammatory and immune mechanisms; and improvement of animal models that are more relevant for human disease.

Original language	English (US)
Pages (from-to)	792-798
Number of pages	7
Journal	American journal of respiratory and critical care medicine
Volume	171
Issue number	7
DOIs	https://doi.org/10.1164/rccm.200409-1205WS
State	Published - Apr 1 2005

ASJC Scopus subject areas

Pulmonary and Respiratory Medicine
Critical Care and Intensive Care Medicine

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1164/rccm.200409-1205WS

Cite this

Fink, J. N., Ortega, H. G., Reynolds, H. Y., Cormier, Y. F., Fan, L. L., Franks, T. J., Kreiss, K., Kunkel, S., Lynch, D., Quirce, S., Rose, C., Schleimer, R. P., Schuyler, M. R., Selman, M., Trout, D., & Yoshizawa, Y. (2005). Needs and opportunities for research in hypersensitivity pneumonitis. American journal of respiratory and critical care medicine, 171(7), 792-798. https://doi.org/10.1164/rccm.200409-1205WS

@article{dee8e540e75240b89a880e54cbb3bda7,

title = "Needs and opportunities for research in hypersensitivity pneumonitis",

abstract = "Hypersensitivity pneumonitis (HP) develops after inhalation of many different environmental antigens, causing variable clinical symptoms that often make diagnosis uncertain. The prevalence of HP is higher than recognized, especially its chronic form. Mechanisms of disease are still incompletely known. Strategies to improve detection and diagnosis are needed, and treatment options, principally avoidance, are limited. A workshop recommended: a population-based study to more accurately document the incidence and prevalence of HP; better classification of disease stages, including natural history; evaluation of diagnostic tests and biomarkers used to detect disease; better correlation of computerized tomography lung imaging and pathologic changes; more study of inflammatory and immune mechanisms; and improvement of animal models that are more relevant for human disease.",

author = "Fink, {Jordan N.} and Ortega, {Hector G.} and Reynolds, {Herbert Y.} and Cormier, {Yvon F.} and Fan, {Leland L.} and Franks, {Terl J.} and Kathleen Kreiss and Steven Kunkel and David Lynch and Santiago Quirce and Cecile Rose and Schleimer, {Robert P.} and Schuyler, {Mark R.} and Moises Selman and Douglas Trout and Yasuyuki Yoshizawa",

year = "2005",

month = apr,

day = "1",

doi = "10.1164/rccm.200409-1205WS",

language = "English (US)",

volume = "171",

pages = "792--798",

journal = "American journal of respiratory and critical care medicine",

issn = "1073-449X",

publisher = "American Thoracic Society",

number = "7",

}

Fink, JN, Ortega, HG, Reynolds, HY, Cormier, YF, Fan, LL, Franks, TJ, Kreiss, K, Kunkel, S, Lynch, D, Quirce, S, Rose, C, Schleimer, RP, Schuyler, MR, Selman, M, Trout, D & Yoshizawa, Y 2005, 'Needs and opportunities for research in hypersensitivity pneumonitis', American journal of respiratory and critical care medicine, vol. 171, no. 7, pp. 792-798. https://doi.org/10.1164/rccm.200409-1205WS

TY - JOUR

T1 - Needs and opportunities for research in hypersensitivity pneumonitis

AU - Fink, Jordan N.

AU - Ortega, Hector G.

AU - Reynolds, Herbert Y.

AU - Cormier, Yvon F.

AU - Fan, Leland L.

AU - Franks, Terl J.

AU - Kreiss, Kathleen

AU - Kunkel, Steven

AU - Lynch, David

AU - Quirce, Santiago

AU - Rose, Cecile

AU - Schleimer, Robert P.

AU - Schuyler, Mark R.

AU - Selman, Moises

AU - Trout, Douglas

AU - Yoshizawa, Yasuyuki

PY - 2005/4/1

Y1 - 2005/4/1

N2 - Hypersensitivity pneumonitis (HP) develops after inhalation of many different environmental antigens, causing variable clinical symptoms that often make diagnosis uncertain. The prevalence of HP is higher than recognized, especially its chronic form. Mechanisms of disease are still incompletely known. Strategies to improve detection and diagnosis are needed, and treatment options, principally avoidance, are limited. A workshop recommended: a population-based study to more accurately document the incidence and prevalence of HP; better classification of disease stages, including natural history; evaluation of diagnostic tests and biomarkers used to detect disease; better correlation of computerized tomography lung imaging and pathologic changes; more study of inflammatory and immune mechanisms; and improvement of animal models that are more relevant for human disease.

AB - Hypersensitivity pneumonitis (HP) develops after inhalation of many different environmental antigens, causing variable clinical symptoms that often make diagnosis uncertain. The prevalence of HP is higher than recognized, especially its chronic form. Mechanisms of disease are still incompletely known. Strategies to improve detection and diagnosis are needed, and treatment options, principally avoidance, are limited. A workshop recommended: a population-based study to more accurately document the incidence and prevalence of HP; better classification of disease stages, including natural history; evaluation of diagnostic tests and biomarkers used to detect disease; better correlation of computerized tomography lung imaging and pathologic changes; more study of inflammatory and immune mechanisms; and improvement of animal models that are more relevant for human disease.

UR - http://www.scopus.com/inward/record.url?scp=20144388635&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=20144388635&partnerID=8YFLogxK

U2 - 10.1164/rccm.200409-1205WS

DO - 10.1164/rccm.200409-1205WS

M3 - Review article

C2 - 15657460

AN - SCOPUS:20144388635

SN - 1073-449X

VL - 171

SP - 792

EP - 798

JO - American journal of respiratory and critical care medicine

JF - American journal of respiratory and critical care medicine

IS - 7

ER -

Needs and opportunities for research in hypersensitivity pneumonitis

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this