Neighborhood disorder predicts lower serum vitamin D levels in pregnant African American women: A pilot study

J. Woo*, M. D. Koenig, C. G. Engeland, M. A. Kominiarek, R. White-Traut, P. Yeatts, C. Giurgescu

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Pregnant African American women are more likely to live in neighborhoods with more disorder (e.g., vacant housing, littler, crime) and to have vitamin D deficiency due to their darker skin pigmentation and poor production of vitamin D [25(OH)D] from ultraviolet rays. However, no study has examined the potential link between neighborhood disorder and 25(OH)D status in African American pregnant women. Forty-one pregnant African American women completed validated questionnaires about perceived neighborhood disorder (6 items; 3-point scale; range 6–18) and with concurrent serum levels of 25-hydroxyvitamin D [25(OH)D] assessed during pregnancy at 18–24 weeks gestation. Higher levels of perceived neighborhood disorder were associated with lower levels of serum 25(OH)D. Pregnant African American women who report higher disorder in their neighborhood may spend less time outside. Health care providers should include assessment of perceived neighborhood disorder. Future research needs to evaluate the relationships among neighborhood disorder and 25(OH)D levels among pregnant African American women.

Original languageEnglish (US)
Article number105648
JournalJournal of Steroid Biochemistry and Molecular Biology
Volume200
DOIs
StatePublished - Jun 2020

Funding

This research was supported in part by the University of Illinois at Chicago CCTS Pilot Grant “Pathways to Preterm Birth: Stress, Inflammation & Cervical Remodeling” Award number CCTS0811-02 , the CCTS0811-02, the Irving Harris Foundationand , and the Robert Wood Johnson Foundation Nurse Faculty Scholars program # 72117 ; Also This research was supported by funding from the National Institute on Minority Health and Health Disparities ( U54 MD012523 ) Subaward (088917). The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Institute on Minority Health and Health Disparities; the National Institutes of Health; or the U.S. Department of Health and Human Services. This research was supported in part by the University of Illinois at Chicago CCTS Pilot Grant ?Pathways to Preterm Birth: Stress, Inflammation & Cervical Remodeling? Award number CCTS0811-02, the CCTS0811-02, the Irving Harris Foundationand, and the Robert Wood Johnson Foundation Nurse Faculty Scholars program #72117; Also This research was supported by funding from the National Institute on Minority Health and Health Disparities (U54 MD012523) Subaward (088917). The views expressed in this manuscript are those of the authors and do not necessarily represent the views of the National Institute on Minority Health and Health Disparities; the National Institutes of Health; or the U.S. Department of Health and Human Services.

Keywords

  • Neighborhood disorder
  • Pregnancy
  • Vitamin D

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Biochemistry
  • Molecular Medicine
  • Molecular Biology
  • Endocrinology
  • Clinical Biochemistry
  • Cell Biology

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