Neonatal Lupus

What We Have Learned and Current Approaches to Care

Marisa S Klein-Gitelman*

*Corresponding author for this work

Research output: Contribution to journalReview article

7 Citations (Scopus)

Abstract

Neonatal lupus results from the passive transfer of autoantibodies; however, this transfer is not sufficient to cause disease. This article reviews clinical presentation with a focus on autoimmune-mediated congenital heart disease. Recent data looking for additional disease mechanisms and biomarkers as well as latest information on interventions will be reviewed. Our understanding of this rare disease is often dependent on patient participation in disease registries and biorepositories. Future participation in registries including descriptive as well as biophysical data is critical to our knowledge.

Original languageEnglish (US)
Article number60
JournalCurrent Rheumatology Reports
Volume18
Issue number9
DOIs
StatePublished - Sep 1 2016

Fingerprint

Registries
Patient Participation
Rare Diseases
Autoantibodies
Heart Diseases
Biomarkers
Neonatal Systemic lupus erythematosus

Keywords

  • Autoimmune-mediated congenital heart disease
  • Neonatal lupus
  • Passive immune injury
  • Patient registries

ASJC Scopus subject areas

  • Rheumatology

Cite this

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abstract = "Neonatal lupus results from the passive transfer of autoantibodies; however, this transfer is not sufficient to cause disease. This article reviews clinical presentation with a focus on autoimmune-mediated congenital heart disease. Recent data looking for additional disease mechanisms and biomarkers as well as latest information on interventions will be reviewed. Our understanding of this rare disease is often dependent on patient participation in disease registries and biorepositories. Future participation in registries including descriptive as well as biophysical data is critical to our knowledge.",
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Neonatal Lupus : What We Have Learned and Current Approaches to Care. / Klein-Gitelman, Marisa S.

In: Current Rheumatology Reports, Vol. 18, No. 9, 60, 01.09.2016.

Research output: Contribution to journalReview article

TY - JOUR

T1 - Neonatal Lupus

T2 - What We Have Learned and Current Approaches to Care

AU - Klein-Gitelman, Marisa S

PY - 2016/9/1

Y1 - 2016/9/1

N2 - Neonatal lupus results from the passive transfer of autoantibodies; however, this transfer is not sufficient to cause disease. This article reviews clinical presentation with a focus on autoimmune-mediated congenital heart disease. Recent data looking for additional disease mechanisms and biomarkers as well as latest information on interventions will be reviewed. Our understanding of this rare disease is often dependent on patient participation in disease registries and biorepositories. Future participation in registries including descriptive as well as biophysical data is critical to our knowledge.

AB - Neonatal lupus results from the passive transfer of autoantibodies; however, this transfer is not sufficient to cause disease. This article reviews clinical presentation with a focus on autoimmune-mediated congenital heart disease. Recent data looking for additional disease mechanisms and biomarkers as well as latest information on interventions will be reviewed. Our understanding of this rare disease is often dependent on patient participation in disease registries and biorepositories. Future participation in registries including descriptive as well as biophysical data is critical to our knowledge.

KW - Autoimmune-mediated congenital heart disease

KW - Neonatal lupus

KW - Passive immune injury

KW - Patient registries

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U2 - 10.1007/s11926-016-0610-z

DO - 10.1007/s11926-016-0610-z

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