Neonatal Sepsis in the Emergency Department

Daniel T Robinson, Praveen Kumar, Sandra B. Cadichon*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Despite significant improvements in the care and management of acutely ill infants, septicemia remains one of the top 10 causes of neonatal death. Neonates can present either shortly after birth or later with subtle signs to suggest infection. Early diagnosis and prompt intervention are essential to prevent serious morbidity and mortality in neonates (<28 days of age) and infants (>28 days of age) with sepsis. Unlike older children, a young infant is often incapable of demonstrating clinical evidence of illness, and even a "well-appearing" infant may have a bacterial or viral disease. The immaturity of the newborn's immune system may increase the susceptibility of these patients to infections. The following article is a review of the clinical presentation, differential diagnosis, and evaluation and management of a neonate presenting to the emergency department with suspected sepsis.

Original languageEnglish (US)
Pages (from-to)160-168
Number of pages9
JournalClinical Pediatric Emergency Medicine
Issue number3
StatePublished - Sep 1 2008


  • bacterial and viral infection
  • emergency department
  • immune system
  • neonatal sepsis

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Emergency Medicine


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